Topic > Newt's regeneration cures eye diseases - 2130

Newt's regeneration as a basis for the permanent cure of eye diseases Sight is one of the most used senses, often taken for granted. Damage to the eyes can vary, both from external factors. A punch in the eye can permanently damage the lens and retina. Physical injuries are numerous. Eyes can be permanently blinded by incorrect placement of chemicals or an out-of-control spark from a campfire. Diseases such as glaucoma and macular degeneration can lead to permanent blindness. On the other hand, newts can regenerate any organ, including eyes, once it has been damaged. As stated by Catarina Franco, “Regeneration is a complex cellular process by which, instead of simply forming a scar following an injury, the animal forms new functional tissue” (Franco, 2013). Research is underway on the regeneration process of newts using stem cells as substitutes to achieve the same results in humans. Eyes are important, so a lifelong cure using newt regeneration should be available to humans through the use of stem cells or other regenerative processes. Human eyes have a complex system for transmitting images to the brain so it can understand an image. There are three important layers in an eye: the cornea, the lens and the retina. Light waves enter through the cornea, pass the lens and then hit the retina, where photoreceptors signal the image to the optic nerve (Chiba, 2013). The optic nerve transmits the image, as data, to the brain and converts it into a complete image. Between the cornea and the lens are the iris and the pupil. The iris surrounds the pupil, an opening in the eye that leads to the lens. Together, the pupil and the lens regulate the amount of light entering the eye. If part of the eye is damaged in any way, if...... center of paper ......s, MM, Yamada, S., ... & Del Rio-Tsonis, K. Gene control loss of function in newts with emphasis on lens regeneration. natural protocols, 2011, 6, 593-599.Tsonis, P. A. and Del Rio-Tsonis, K. Lens and retina regeneration: transdifferentiation, stem cells and clinical applications. Experimental Eye Research, 2004, 78, 161-172. Wassmer, S., Beddaoui, M., Rajai, P., Munger, R., and Tsilfidis, C. A focus on the optical properties of the regenerated Newt lens. PloS one, 2013, 8, e70845.Yang, XT, Bi, YY, Chen, ET, and Feng, DF Overexpression of Wnt3a facilitates proliferation and neural differentiation of neural stem cells in vitro and after transplantation into the rat retina wound. Journal of Neuroscience Research, 2014, 92, 148-161.Yip, HK Retinal stem cells and regeneration of the visual system. Anatomical documentation, 2014, 297, 137-160.