Humans have used plants, plant constituents, herbal preparations and finished herbal products for hundreds of years, among others as foods, as meditative agents as stimulants , narcotics and hallucinogens for wearing and shelter as aromatic substances, cosmetics, dyes and for organizing toxic arrows and spearheads for warfare and research. Increasing knowledge about the chemical structures and mechanisms of action of the pharmacologically active ingredients of such substances has led to the development of a variety of life-saving drugs against human diseases. Examples are medicines against vascular disorders, such as cardiovascular disorders, such as digoxin from digitalis Digitalis purpura L. (Scrophulariaceae) and reserpine from Indian snakeroot Rauwolfia serpentine (L.) Benth. ex Kurz (Apocynaceae) [1] antineoplastic agents such as vincristine from the periwinkle plant Catharanthus roseus (L.) G.Don (Apocynaceae) [2] and paclitaxel from the Pacific yew Taxus brevifolia Peattie 1950 (Taxaceae) [3] hypoglycemic agents such as metformin from the French lilac Galega officinalis L. (Fabaceae) [4] and antibiotics such as penicillin from the fungus Penicillium notatum (Trichocomaceae) [5]. Over half a century of overall drug discovery and development has enabled the creation of numerous useful drugs, as well as a wide range of successes in the treatment and management of human disease. Some examples are provided above. However, there is a pressing demand for many effective drugs. Despite the provision of a formidable array of drugs, malignant, diabetic, airway and infectious diseases are still among the major causes of morbidity and mortality in different parts of the world [6]. Herbal medicines are the combination of... middle of the paper... dictated by the needs of the body, compared to the amount of treatment. Secondly, it should channel the active entity of the herbal drug to the place of action. Conventional dosage forms, including extended-release dosage forms, are unable to meet any of these [12]. The new drug delivery system used with herbal medicine should be able to channel the active entity of the herbal drug to its site of action at a rate directed by the body's needs/chronopharmacology of the disease throughout the duration of treatment. Various NDDS which are used in herbal medicine and phytochemicals are also broadly classified into the following groups [13]:1. Vascular delivery systems including liposomes, ethosomes, phytosomes, transferosomes.2. Particulate delivery systems including microspheres, nanoparticles, micropellets.3. Biphasic systems, such as micro/nano emulsions.