In this experiment, the vaccine contains three virus strains, A/Panama, A/New Caledonia and B/Shangdong. A significant increase in antibody responses to the A/Panama strain was demonstrated in women exposed to physical and mental stress immediately before vaccination with the influenza strain compared to controls. Importantly, this finding expanded the findings of animal studies in which acute stress enhances the antibody response to immunization (Silberman, Wald, and Genaro (2003); Persoons et al (1995)). However, in this case there was no evidence of a higher antibody response in men