IndexIntroductionStages of Alzheimer's DiseaseRisk Factor of Alzheimer's DiseaseDiagnosis of Alzheimer's DiseaseConclusionAlzheimer's Disease is a disease of intelligence in which our cells of understanding break down to connect all the others have difficulty to speak and cause confusion when a task performed by the patient because because a greater amount of rubbery and twisted proteins is offered between the brain cells, as a result the cells fail to convey the message. This disease manifests itself step by step in the initial stage, the doctor is unable to diagnose the disease. Almost at the fourth essay this disease was diagnosed completely. In this disease the patient loses consciousness from his environment. Stress, high sugar level, obesity, heredity and poor education are the main factors of Alzheimer's disease. Nowadays many people suffer from this disease but there is no specific diagnosis of this disease but some tests like PET, CT scanner, MMSE and MRI test can diagnose. Some labs and blood tests can also diagnose it. There is no treatment for Alzheimer's disease, but some drugs such as cholinesterase and nemantine are used to treat this disease. Certain nutrients and regular exercise also play an important role in treating Alzheimer's disease. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essayKeywordsAlzheimer's disease, patients, depression, plaques and tanglesIntroductionAlzheimer's disease is a mental illness in which the fall of the section alone suggests the origin of the defeat of the memory, the obstacle to the decision the word, the changes of mood, enduring with amazement once the daily activities and the repetitive mind of Alzheimer's disease is the overall daily cause of dementia, a set of common sense disorders that cause the deficiency of intellectual and group abilities in the frequent elderly. In intelligence it questions plaques and tangles that instigate the memory of defeat. (Ahmed A et al 2013) the doctor Alois Alzheimer discovered the ad while he was examining for a long time a serene woman Auguste D, who had a medical condition in, napping disorders, memory turbulence, aggression, crying and progressive confusion. (Reger B 2002). It formed dense deposits around his nerve cells. Alzheimer, who was a German neurologist and psychiatrist, noticed abnormal deposits in the case of a 51-year-old woman suffering from dementia. It has now been found that Alzheimer's disease patients contain many common sense abnormalities called plaques and tangles. (Hippius H and Neundörfer G, 2003). Plaques and tangles called beta amyloid and tau interrupt the transfer between nerve cells and the mind. a fraction of the mutilation as a result the mind is able to not carry out habitual behaviors such as thinking, eating, sitting, speaking and other functions that the container does not normally perform. (Morae AHC et al, 2013) currently more than 25 million communities are in misery of Alzheimer's disease in the world and 4.6 million nations expand throughout the year (Ahmed A et al 2013). Pakistan is a growing country and is estimated to become the third most densely populated country in the world by 2050 (Khan Q, 2017). In Pakistan, it strengthens the hope of living, the rate of Alzheimer's disease is too better. In Pakistan, nearby, there are no precise records about Alzheimer's disease which are short of exploring and living where one is sick with this disease due to lack of awareness. To master this disease it is possible to undertake someinfluential steps. (Seetlani NK, 2016). People suffering from Alzheimer's disease give birth to extremely significant plaques and tangles. Plaques are the set of proteins that arise intermediate between the faction and tangles are any other twisted proteins that form inside cells (Farley P,2013). When a self is further aged, at that time the concentration of plaques and tangles are better. They discourage transfer between nervous compartments and in response initiate memory defeat, the problem of acting on everyday behavior and the like (Hardy J 2006) the understanding is calm of 100 billion nervous cubicles and each nervous cubicle is united to a new nervous cabal for email, for faith and practices around others, they act as soon as these plaques and tangles fill up, they affect the nervous chamber, these mutilations take place in the hippocampus in the work of reason which is responsible for wisdom accepted and causes Alzheimer's Alzheimer's disease.(Agdeppa ED,Kepe V,Liu j et al 2001).Stages of Alzheimer's diseaseAt this point a character is pretty much average and does not show any symptoms of Alzheimer's disease.No healthcare profession shows symptoms of Alzheimer's disease. In this phase where the human being is put together in everyday life. For the stage of any meeting of the day they do not need the help of other people. (Albert M 1994). In mild cognitive decline some symptoms emerge and common mood changes emerge in this period, but the curative examination also does not reveal that the person suffering from Alzheimer's disease suffers from short-term memory loss, such as when talking to others they forget some words, what they want to say to others and they also forget where they kept something. But at this stage, as time passes, they remember all things and remain normal, perform their function normally. Even at this stage this disease is not diagnosed. People with early Alzheimer's disease may have difficulty performing functions such as planning, the organizational ability to solve a problem and manage a difficult situation, but remain independent of others and have no need to help others (Albert MS, Heller HS , Milberg W. 1988). It is the early stage of diagnosis where Alzheimer's disease can be detected, but it is a difficult stage to detect. In this phase, symptoms may appear but not Alzheimer's disease, which is diagnosed in all patients but only in some. patients (Shahmiri, E.et al 2017). Alzheimer's disease can be detected. At this stage the problem of memory loss occurs, do not judge anything (Wattmo C et al 2016). When a person reads something, forgets what I read, the person repeats the same question again and again. The person faces many difficulties when making a plan and sometimes they forget their name when facing new people or during a meeting because they are confused and not facing new people. And at this stage the family member and friend can notice all these things. At this stage the doctor can detect Alzheimer's disease, PET scan and other tests can detect Alzheimer's disease. (Albert M. 1994) It is a mild or early stage of Alzheimer's disease. At this stage a person has clear signs and symptoms of Alzheimer's disease because at this stage everyone can notice the signs and symptoms and at this stage Alzheimer's disease can be easily detected by PET test. In this stage a person has fear whether society selects him or not in this environment (fear of rejection), lack of responsiveness where he cannot respond to any problem, loss of intellectual capacity where they cannotsolve simple questions or answer simple questions (Albert M 1994). They find it difficult when carrying out normal or daily routine tasks, and sometimes they forget their history and do not know who they are, what is their name? All these symptoms appear in this stage, they face many problems in their life and doctor easily detects Alzheimer's disease in this stage. (Wattmo C et al 2016) It is an intermediate stage of Alzheimer's disease. A person may no longer be able to carry out normal daily activities such as dressing or bathing. At this stage a person feels confused and does not know where he is and what day it is? He needs to help others choose dressing according to the season (Tarawneh R and Holtzman DM, 2012). The person further suffers from problems of loss of memory, mental activity and also loses the ability to solve any problem he encounters. They are unable to solve a problem and do not perform their daily living functions. In every field of life they face problems because they do not show normal behavior. (Suthers K,2003) It is a severe or advanced stage Alzheimer's disease. At this stage the person is totally unable to respond to his environment because it is the last stage of Alzheimer's disease. The person needs help to respond to environmental changes and also needs help to carry out daily activities such as eating, drinking, sitting etc. You may lose the ability to talk, walk or smile without help. He needs a nurse to help patients who eat, drink and sit. They lose the ability to speak during the sentence or briefly explain any problem in one word. These stages are very serious for that person. (Tarawneh R and Holtzman DM, 2012). Risk Factors of Alzheimer's Disease There are many factors that cause Alzheimer's disease, such as a history of diabetes, depression, smoking, obesity, family history, and lower education. Chen ST et al (2014). Type II diabetes is the main consequence of the dynamics of Alzheimer's disease as it causes reserves of Aβ in the mental compartment and is unable to exploit insulin in the quantity or insulin not correct for the purpose in association if a person is overweight every these cases occur (Alford S et al 2017) and the cells do not return to insulin, so the glucose heads towards multiplication which leads to an increase in blood pressure and, in due course, triggers Alzheimer's disease . (Sultana N, 2011) Smoking is too valid diabetes and countless other diseases such as cancer, cardiovascular diseases (Anstey kj, 2007). 45% of smokers are at risk of developing dementia compared to non-smokers. The ex-smoker (a big cheese who was good at quitting smoking) knows how to reduce the effects of Alzheimer's disease by not smoking. Cigarette smoking is linked to billboard neuropathology in preclinical models and humans. (Durazzo.CT 2014) Cigarette smoking tolerates pollutants that promote oxidative stress and inflammation, which are also linked to the increase in Alzheimer's disease. Human beings who smoke a cigarette also have their internal system awakened and these also have the risk of causing Alzheimer's disease (Anstey kj, 2007). Depression caused 20-40% of those affected by Alzheimer's disease. Greater risk of depression originates in women than men, so women are more affected by Alzheimer's disease. Those events that cause depression such as lack of social support where society can support the person, stressful life events such as economic stress where one does not get enough salary to satisfy one's desire, isolation and loneliness. These are all the reasons that is the causeof depression and, in due course, influences Alzheimer's disease. (Usman S et al 2010). Depression is the end product of understanding groups that age further and are afflicted with a greater risk of developing Alzheimer's disease. (Ownby R L.et al.2006). Obesity or being overweight is also a risk factor of Alzheimer's disease because obesity or being overweight causes increased blood pressure and increased blood pressure causes Alzheimer's disease. A higher body mass index measures obesity and overweight in people .when a person is obese or overweight, then they have higher blood pressure and have a higher risk of developing diabetes and we know that diabetes causes the disease of Alzheimer's. (Usman S et al, 2010). Parents contain apolipoproteins in DNA in total up to 9. possess two patterns ApoE -e2 and ApoE_e3 mutually parents pass one DNA to offspring if correct until metamorphosis one parent both transfer DNA to offspring after which affect Alzheimer's disease Apolipoprotein E is a set of proteins involved in the lion's share of fat metabolism (Roses AD,1996). ApoE is cholesterol and fat moving in understanding at that time cholesterol and fat accumulate side by side in plump or heavily caused federation, so in this mode they give rise to Alzheimer's disease. The qualities that APOE-e4 RNA contains give rise to an additional risk of developing Alzheimer's disease compared to individuals who do not possess this gene. (Caselli, JR 2013). Poor education is also a risk factor for Alzheimer's disease. They mainly run the risk of are found in less educated people (Sharp ES and Gatz M 2011) who have no awareness of this disease and. Mentally functioning people are not diagnosed with Alzheimer's disease compared to individuals who are not mentally active. a pancake creates a synaptic link in the intellect and plays a key role in memory formation. These associations enter a neural network as a neuronal connection with an alternative neuron. If this disease advances in the carcass and damage to the neurons occurs (Usman S et al 2010). Diagnosing Alzheimer's Disease Alzheimer's disease can be diagnosed through family interviews, knowing the patient's history, physical exams of the patient, and some neuroimaging tests. Measurement of biomarkers also play an important role in the diagnosis of Alzheimer's disease. (Feldman HH et al, 2008). Influence/role of biomarkers Biomarkers play an important role as an indicator in the measurement and evaluation of biological process and pharmacological responses. (Colburn et al, 2000). Biomarkers also play an important role in the diagnosis of Alzheimer's disease. (Blennow, 2010)Neuropsychological tests: Neuropsychological tests used to diagnose MCI and dementia. In recent research, neuropsychological tests are used to diagnose MCI. (Albert et al, 2011). depend on four cognitive domains: attention, memory, language and visuospatial functions. (Gorelick et.al,2011).Neuropsychological tests and recreation are an essential element in cognitive disorders of a particular person (Albert et.al,2011).MRI Test: Magnetic resonance imaging test is the most popular test in diagnosis early Alzheimer's disease. (Wolz.R et.al,2011). In MRI test, strong radioactive waves and magnets are used to reproduce the detailed view or to get the detailed image of the brain so that the disease can be diagnosed. For the MRI test, the part of the medial temporal lobe is used because it is the most discriminating MIR measurement. (Richard.E et.al 2012). Can.