Nanotechnologies, particularly nanofibers, have attracted interest in tissue engineering applications [1]. The large surface area to volume ratio is the unique property of nanofibers, which enables cell migration and proliferation in tissue engineering scaffolds [2]. The scaffold can be fabricated by several methods including solvent casting, particle leaching, phase separation, emulsion freeze drying, 3D printing technique and many others [3]. However, the simplicity of electrospinning provides an advantage for the construction of nanofibrous scaffolds [4]. Electrospinning is the most efficient method to fabricate continuous nanofibers from both synthetic and natural polymers. This method can produce polymer fibers with diameters ranging from micrometers up to nanometers [5]. Since most of the extracellular matrix (ECM) of natural tissues is composed of a cross-linked network of collagen fibrils with diameters between 15 µm and 5 nm, in which human cells are deposited and organized around these fibrils [6] . Therefore, the electrospinning technique has attracted interest in artificial im...